Lloyd Marks, MD, FACC

LLOYD MARKS, MD, MBA, FACC

Contact Information
Lloyd Marks, MD, FACC

This early stage startup company is commercializing a new medical monitoring device, the "Pulse Flowmeter" which provides an early warning sign of impending shock, before blood pressure falls. I am the inventor of the technology. (www.mgimedical.com)

Specialized in Pediatric and Adult Congenital Heart Disease

Services included clinical evaluation, electrocardiography, echocardiography, stress testing, Holter/event monitoring, diagnostic cardiac catheterization and interventional cardiac catheterization

EDUCATION:

2016 - MBA, Haslam School of Business, University of Tennessee Physician Executive MBA Program

1971 - B.S. Electrical Engineering. Massachusetts Institute of Technology; major field index 5.0/5.0

1976 - M.D., University of Michigan Medical School

POSTDOCTORAL CLINICAL TRAINING:

1976 ‑ 1977 - Pediatrics Resident PL‑1, University of California, San Diego

1978 ‑ 1979 - Pediatrics Resident PL‑2, PL‑3, Children's Hospital National Medical Center, Washington, D.C.

1980 ‑ 1983 - Fellow in Pediatric Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD.

ADDITIONAL GRADUATE EDUCATION:

1993 - 1994 - Drexel University - 3 graduate courses (10 credits) in engineering mathematics 4.0/4.0 index, non-matriculated

2000 - 2002 - Rutgers University - 4 graduate courses (12 credits) in medical instrumentation, digital signal processing, modeling of biologic systems and computation - 4.0/4.0 index, non-matriculated

CERTIFICATION:

1977 - Diplomate, National Board of Med Examiners (#168085)

1980 - Diplomate, American Board of Pediatrics (#24583)

1985 - Diplomate, Sub‑Board of Pediatric Cardiology (#0744)

LICENSURE:

1977 - District of Columbia Medical License (#10616)

1980 - Maryland State Medical License (#D24596)

1983 - New York State Medical License (#155825)

1986 - Pennsylvania State Medical License (#MD‑036389‑E)

1994 - New Jersey State Medical License (#61495)

HONORS:

1971 - National Science Foundation Commendation

1971 - Tau Beta Pi Engineering Honorary

1971 - Eta Kappa Nu Electrical Engineering Honorary

1971 - Sigma Xi Research Honorary

2016 - Physician Leader of the Year Award, Haslam School of Business, University of Tennessee

HOSPITAL POSITIONS/APPOINTMENTS:

1983 - 1986 - Staff Pediatric Cardiologist, University Hospital, State University of New York at Stony Brook, Stony Brook, NY

1986 - 1994 - Director of the Cardiovascular Laboratory, St. Christopher's Hospital for Children, Philadelphia, PA (facility where 10 pediatric cardiolo­gists per­formed over 350 procedures annually with the assistance of 5 full time staff). Privileges reactivated in 1999.

1994 - 1997 - Chief, Division of Pediatric Cardiology, The Children's Hospital of New Jersey, Newark, NJ (The division consisted of 4 full-time and 1-part time pediatric cardiologists and a staff of 15 support personnel).

Current (1997 - ) - St. Barnabas Medical Center, Livingston, NJ

Current (1997 - ) - JFK Medical Center, Edison, NJ

Current (1998 - ) - St. Joseph's Medical Center, Paterson, NJ

ACADEMIC APPOINTMENTS:

1983 ‑ 1986 - Assistant Professor of Pediatrics, State University of New York at Stony Brook, Stony Brook, NY.

1983 ‑ 1986 - Assistant Professor of Electrical Engineering, State University of New York at Stony Brook, Stony Brook, NY.

1986 - 1991 - Assistant Professor of Pediatrics, Section of Pediatric Cardiology, Temple University School of Medicine, Philadelphia, PA.

1991 - 1994 - Associate Professor of Pediatrics, Section of Pediatric Cardiology, Temple University School of Medicine, Philadelphia, PA.

1988 - 1994 - Adjunct Professor of Biomedical Engineering, Drexel University, Philadelphia, PA.

Current (1996 - ) - Clinical Associate Professor of Pediatrics, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey

Current (1998 - ) - Adjunct Associate Clinical Professor, Mt. Sinai Medical School, New York, NY

Current (2013 - ) - Adjunct Professor of Biomedical Engineering, Rutgers University, Piscataway, NJ.

TEACHING EXPERIENCE:

As a clinical attending at teaching institutions for 15 years, I taught hundreds of medical students, residents, and pediatric cardiology fellows via didactic lectures, daily rounds, a core departmental lecture series, a core divisional lecture series, and one-on-one interaction.

As a bioengineer/researcher I have mentored more than 40 engineering students in the design, and particularly the user interface, of a wide variety of medical devices, some of which have been used in successful clinical trials (as noted in publications section).

As a clinical researcher, I mentored most of the St. Christopher’s/Temple pediatric cardiology fellows particularly in experimental design and statistics; I co-authored papers with 5 of the fellows (Abdallah, Singh, Levchuck, Stauffer, Marangi).

I organized a statistics course for the entire St. Christopher’s Hospital for Children fellowship program.

PEDIATRIC CARDIOLOGY FELLOWS TRAINED:

Hema Bhargava, MD (1 year) - Currently a board certified pediatric cardiologist on staff of the Children’s Hospital of Philadelphia, Philadelphia, PA

Anthony Rossi, MD (2 years) - Currently a board certified pediatric cardiologist and the Director of the Pediatric Cardiac Intensive Care Unit, Newark Beth Israel Medical Center, Newark, NJ

Barbara Lane, MD (2 years) - Currently in private practice in Philadelphia suburbs

Donald Marangi, MD (3 years) - Currently a board certified pediatric cardiologist and pediatric electrophysiologist on staff of The University of Florida, Jacksonville, FL

Hasan Abdallah, MD (3 years) - Currently a board certified pediatric cardiologist in private practice in suburban New Orleans

Nina Sandhu, MD (3 years) - Currently a board certified pediatric cardiologist and Director of Interventional Pediatric Cardiology at Tulane University, New Orleans, LA

Gautam Singh, MD (3 years) - Currently a board certified pediatric cardiologist on staff at St. Louis Children’s Hospital, St. Louis, MO

Paul Stephens, MD (3 years) - Currently a board certified pediatric cardiologist on staff of the Children’s Hospital of Philadelphia, Philadelphia, PA

Sharon Weil - (1 year) - Currently a board certified pediatric cardiologist in private practice in Philadelphia

Nancy Stauffer, MD (2 years) - Currently a board certified pediatric cardiologist in private practice, Atlanta, GA

Sean Levchuk, MD (2.5 years) - Currently a board certified pediatric cardiologist in private practice in Manhasset, NY

GRANT SUPPORT:

1997 - 1998 - Datascope Corporation, Clinical Trial of Accutor Noninvasive Blood Pressure Device - Grant # P-10 - Direct Costs - $10,000

1997 - 1998 - UMDNJ Foundation, Detection of Hypovolemia with Pulse Volume Analysis, - Grant # 18-98 - Direct Costs - $37,000

1990 - 1991 - Biomedical Research Support Grant (Temple University) $20,000

1987 - 1989 - Academic Development Fund (Temple University) $20,000

1983 - 1986 - Biomedical Research Support Grant (State University of New York) $20,000

1981 - 1983 - Maryland Heart Association Traineeship $36,000 ($18,000 x 2 years)

EDITORIAL POSITIONS:

1993 - 2000 - Editorial Board, Biomedical Instrumentation and Technology, AAMI, Arlington, VA

1992 - 1995 - Honorary Clinical Editor, Physiological Measurement, Institute of Physics, Bristol, Eng

1993 - current Scientific Editor, Medical Device Research Reports, AAMI, Arlington, VA

OTHER POSITIONS:

1969 ‑ 1971 - Research Assistant, M.I.T. Research Laboratory of Electronics

1971 ‑ 1972 - Design Engineer, Gelman Instrument Corporation, Major Project ‑ Digital Protein Electrophoresis Analyzer, design and prototype

1977 - Staff Fellow, Laboratory of Technical Development, National Heart, Lung, and Blood Institute, N.I.H., Bethesda, MD. Continued development and animal trials of a laser doppler flowmeter

1980 - Research Associate, Department of Infectious Diseases, Children's Hospital National Medical Center, Washington, D.C. I conducted a clinical study evaluating a new antibiotic preparation in the treatment of otitis media.

CONSULTING:

2005 - Datascope - Advised re: decision to purchase company that made external - in-hospital external defibrillator

2001 - Coregis Insurance - Medical malpractice defense case

MAJOR COMMITTEE ASSIGNMENTS:

1990 - Member, Strategic Planning Panel, National Center for Research Resources, National Institutes of Health

1993 - Technical Reviewer, Pennsylvania Department of Commerce Seed Grant Program

1993 - 1994 - Hospital Infrastructure Committee, St. Christopher’s Hospital for Children, Philadelphia, PA

1995 - 1996 - Search Committee for Chief of Pediatric Cardiovascular Surgery, United Hospitals, Newark, NJ

1995 - 1996

  • New Jersey State Cardiac Health Advisory Panel
  • Subcommittee on Cardiac Catheterization
  • Subcommittee on Technology Assessment

LEADERSHIP ROLES AT NATIONAL MEETINGS:

National Meeting Cochair

  • 1989 Annual Meeting of the Association for the Advancement of Medical Instrumentation (AAMI)
  • 1986 AAMI Annual Meeting

Symposium Chair

  • 1994 AAMI Annual Meeting, "Cardiovascular Function and Assist"
  • 1992 AAMI Annual Meeting, "Research Funding for Biomedical Engineering"
  • 1991 AAMI Annual Meeting, "Medical Technology Transfer"
  • 1990 AAMI Annual Meeting, "Interventional Cardiology"
  • 1989 AAMI Annual Meeting, "The Use of Computational Systems in Arrythmia Monitoring, Analysis and Management"
  • 1986 AAMI Annual Meeting, "Applications of Microcomputers in Medicine"
  • 1985 AAMI Annual Meeting, "Innovative Biotechnology: Tracing the Path From Invention to Clinical Use"

Session Cochair

  • 1986 AAMI Annual Meeting, "Microcomputer Technology and Applications"
  • Course Codirector
  • April 1986 AAMI Annual Meeting, "Basics of Electronics and Computers for Physicians"

PUBLICATIONS:

ORIGINAL PEER REVIEWED REPORTS:

1. Collins DL, Marks LA, Edwards D, Kirkpatrick SE, Nyhan WL. Management of Infants with Congenital Diaphragmatic Hernia. West J Med. 1977;127(6):479‑86

2. Rodriquez WJ, Schwartz RH, Sait T, Khan W, Chhabra OP, Gold B, Chang MJ, Reddy S, Marks LA, Gold J, Ruey P, Ross S. Erythromycin‑Sulfisoxazole vs Amoxicillin in the Treatment of Acute Otitis Media in Children. AJD;C. 1985;139(8):766‑70

3. Marks LA. Digital Enhancement of the Peripheral Admittance Plethysmogram. IEEE Trans Biomed Engr. 1987;34(3):192‑198

4. Marks LA, Short KL, Hoffman D, Lew A. Microprocessor Based Robotic System for Control of Fluid Connections in the Cardiac Catheterization Laboratory. IEEE Trans Biomed Engr. 1988; 35(2):161‑6

5. Marks LA, Anaise D, Yland M. Renal Admittance Plethysmography. Proc 14th Northeast Bioengineering Conference. 1988; 14:122-125

6. Marks LA: An Ergonomically Efficient, Descriptive Text Oriented, Microcomputer Based Echocardiogram Measurement and Database System. Proc 16th Northeast Bioengineering Conference. 1990;16:43-4

7. Marks LA, Smith S, Brophy T, Grane R, Moore T. Clinical Application of an Audio Ectopic Beat Detector. Proc 12th Int Conf IEEE EMBS. 1990;12(5):1992-3

8. Marks LA. Medical Technology Transfer: The Inventor's Perspective. Biomed Inst Tech. 1991; 25:35-41

9. Marks LA, Mehta AV, Marangi D. Percutaneous Transluminal Angioplasty of Stenotic Blalock-Taussig Shunts: Effect on Choice of Initial Palliation in Cyanotic Congenital Heart Disease. JACC. 1991; 18(2):546-51

10. Abdallah HI, Karmazin N, Marks, LA. Late Presentation of Misalignment of Lung Vessels. Crit Care Med 1993;21(4):628-30

11. Abdallah HI, Marks LA, Balsara R, Davis D, Russo P. Staged Repair of Pentalogy of Cantrell. Ann Thorac Surg, 1993;56:979-80

12. Marks LA, ed., Wooley M, Miller M, Dunst IP, Thompson CR, Larson A, Rudolph D, Corman J. Advocacy for Biomedical Engineering Seminar. IEEE EMBS Magazine 1993;121(2):25-33

13. Marks LA, Groch AJ. Validation of Variable Width Blood Pressure Cuff. Proc 15th Int Conf IEEE EMBS. 1993;15(2):926-927

14. Abdallah HI, Toomey K, O'Riordan AC, Davidson A, Marks LA. Familial Occurrence of Discrete Subaortic Membrane. Pediatric Cardiology 1994;15:198-200

15. Levchuck S, Marks LA, Robinson B. Intussusception of the Catheter Sheath: A Non-emergency. Pediatric Cardiology. 1995;16:85-86

16. Stauffer NR, Greenberg SB, Marks LA, Singh GK, Siderio DL. Validation of Right Ventricular Volume Measurements by Magnetic Resonance Imaging in Small Hearts Using a Fetal Lamb Model. Investigative Radiology. 1995(Feb);30:87-89

17. Alpert BS, Marks L, Cohen M. K5=Diastolic Pressure. Pediatrics 12/1996;98(5):1002

18. Greenberg SB, Marks LA, Eshaghpour EE. Evaluation of Magnetic Resonance Imaging in Coarctation of the Aorta: The Importance of Multiple Imaging Planes. Ped Cardiology. 8/1997; 18(5):345-9

19. Marks LA, Groch A. Optimizing Cuff Width for Noninvasive Measurement of Blood Pressure. Blood Pressure Monitoring. 2000; 5:153-158

20. Fermi, FS, Marks L. Design of Electrodes for Pulse Volume Measurement/Impedance Plethysmography. Proceedings of the IEEE 26th Annual Northeast Bioengineering Conference. Feb, 2000

PUBLISHED LETTERS:

Davidson A, Marks LA. Shots and Shunts. Pediatric Cardiology 1996;17:132-133

PUBLISHED MEDICAL DEVICE PATENTS:

1. Marks LA. Computer Assisted Admittance Plethysmograph. U.S. Patent Office, Arlington, Virginia. Oct 22, 1985; #4548211

2. Marks LA. Method of and Apparatus for Detecting Cardiac Rhythm Disturbance. U.S. Patent Office, Arlington, Virginia. Nov 15, 1988; #4784153

3. Marks LA. Multi-function Fluid Communication Control System. U.S. Patent Office, Arlington, Virginia. Apr 11, 1989;#4819653

4. Marks LA. Aperture Occlusion Device. U.S. Patent Office, Arlington, Virginia. Apr 28, 1992; #5108420

5. Marks LA. Multilumen Angiography Catheter. U.S. Patent Office, Arlington, Virginia. Jun 16, 1992; #5108420

6. Marks LA. Precision Radiology Scaling Device. U.S. Patent Office, Arlington, Virginia. Sep 22, 1992; #5149965

7. Marks, LA. Fluid Communication Manifold and Control System. U.S. Patent Office, Arlington, Virginia. Dec 8, 1992; #5168901

8. Marks LA. Stereoscopic Fluoroscopy Device. U.S. Patent Office, Arlington, Virginia. Aug 3, 1993; #5233639

9. Marks LA. Calibrated Adjustable Width Blood Pressure Cuff. U.S. Patent Office, Arlington, Virginia. Sep 14, 1993; #5243991

10. Marks LA. Safety Needle and Method of Using Same. U.S. Patent Office, Arlington, Virginia. Oct, 26, 1993; #5256152

11. Marks LA. Multiple Blood Pressure Cuff System. U.S. Patent Office, Arlington, Virginia. May 6, 1997; #5626142

12. Marks LA. Adjustable Blood Pressure Cuff and Method of Using Same. U.S. Patent Office, Arlington, Virginia. May 5, 1998; #5746213

13. Marks LA, Smith M. Signal Averaging Using Gating Signal Obtained from Autocorrela­tion of Input Signals. U.S. Patent Office, Arlington, Virginia. Dec 12, 2006; #7147601

14. Marks LA, Smith M. Signal Methods of Diagnosis Using Pulse Volume Measurement. U.S. Patent Office, Arlington, Virginia. Feb 3, 2009; #7485094

15. Marks LA, Smith M. Method and Device for Measuring Peripheral Vascular Function. Mar 3, 2009; US Patent #7497832

16. Marks LA, Smith M. Impedance Based Device for Non-Invasive Measurement of Blood Pressure and Ankle Brachial Index. Feb 15, 2011; US Patent #7887491

17. Smith M, Marks LA. Peripheral Impedance Plethysmography Electrode and System with Detection of Electrode Spacing. May 17, 2011; US Patent #7945318

18. Marks, LA. Safety needle and method of using same. October 25, 2011; U.S. Patent No. 8,043,268

19. Marks LA, Smith M. Stretch Electrode and Method of Making Physiologic Measurements" US Pat #8019401

20. Marks LA, Smith M. Device for Non-Invasive Measurement of Blood Pressure and Ankle Brachial Index. April 2, 2013;US Patent #8,409,105

21. Marks LA. Safety Needle and Method of Making Same. December 21, 2013. US Patent # 8,617,118

ABSTRACTS:

  • Chang MJ, Rodriquez WJ, Kahn WN, Marks L: Chlamydia Trachomatis in Otitis Media in Children. 20th Interscience Conf on Antimicrobial Agents and Chemotherapy. 1980; 20:526
  • Marks LA, Zahka KG, Kidd L, Cutilletta AF. Oscillatory Waveforms in Forearm Admittance Plethysmography. Ped Res. 1983; 17(4):117A
  • Marks LA, Brinker JA, Zahka KG, Kidd L, Cutilletta AF: Computer Assisted Admittance Plethysmography. Ped Res. 1984; 18(4):127A
  • Marks LA, Brinker JA, Zahka KG, Kidd L, Cutilletta AF. Peripheral Flow Dynamics After Femoral Artery Catheterization Using Computer Assisted Plethysmography. Ped Res. 1984; 18(4):127A
  • Marks LA, Brinker JA, Cutilletta AF. Improving the Measurement of Pulse Volume. AAMI 20th Annual Meeting Proc. 1985; 20:58
  • Marks LA, Smith S, Brophy T, Grane R, Moore T. A Microprocessor Based ECG Analyzer and Tone Generator Which Permits Immediate Recognition and Categorization of Ectopic Rhythms by Sound. JACC. 1989; 13(2):188A
  • Marks LA, Smith S, Brophy T, Grane R, Moore T. A New Audio Monitor for Detecting Ectopic Rhythms: An Algorithm that Generates Sounds with each QRS Complex which Vary with QRS Shape. AAMI 24th Annual Proc. 1989; 24:58
  • Marks LA. Technology Transfer: The Inventor's Perspective. AAMI 25th Ann Proc 1990; 25:48
  • Marks LA, Marangi D, Luks GB. Non-displaced Spherical Reference Object Reduces Error in the Angiographic Measurement of Cardiac Structures. Proc PA Chapter ACC. Sep., 1990
  • Marks LA, Marangi D, Luks GB. Minimizing Error in the Angiographic Estimation of Pulmonary Artery Size. Ped Res. 1990; 27(4):22A
  • Marks LA. Derived Stereo Fluoroscopy. Radiology. 1990; 177(P):254
  • Marks LA, Biancaniello TM. Reversal of Subclavian Steal Following Balloon Angioplasty for Coarctation Restenosis. Proc PA Chapter ACC. Sep., 1991
  • Stauffer NR, Singh GK, Greenberg SB, Marks LA. Validation of Right Ventricular Volumes by Magnetic Resonance Imaging in Fetal Lamb Hearts. Radiology. 1992;189(P):159
  • Singh GK, Yap YS, Delany DP, Monro JL, Keeton BR, Salmon AP, Stauffer NR, Greenberg, BS, Donner RM, Marks LA. Cine MRI Assessment of Right Ventricular Function for Long Term Followup of Primary Repair of Tetralogy of Fallot in Infancy. JACC, Feb 1994; 24A
  • Marks LA, Groch AJ. Improving the Non-Invasive Measurement of Blood Pressure with a New Algorithm for Cuff Width Optimization. AAMI 29th Annual Proceedings. 1990;29:62
  • Marks LA, Groch AJ. Detection of Blood Loss with Digitally Enhanced Admittance Plethysmography. AAMI 29th Annual Proceedings. 1990;29:62
  • Abdallah HI, Culpepper WS, Williams L, Ochsner J, Russo P, Davis DA, Marks LA. Labetalol vs Nitroprusside to Treat Hypertension After Coarctation Repair. Circulation. 1994;90(4)part 2: I-203
  • Greenberg SB, Marks LA, Eshaghpour E. Magnetic Resonance Imaging of Coarctation of the Aorta: Importance of Multiple Imaging Planes. Soc Ped Radiol 37th Annual Proc. Apr 1994
  • Marks LA, Groch AJ. Optimizing Cuff Width for the Noninvasive Measurement of Blood Pressure. Circulation 1994;90(4)part 2: I-616
  • Marks LA, Groch AJ. Early Noninvasive Detection of Hypovolemia Secondary to Acute Blood Loss Using Pulse Volume Analysis. JACC 1995 Feb;25:23A-24A
  • Marks LA. The Effect of the Physical Properties of a Blood Pressure Cuff upon the Accuracy of Non-Invasive Blood Pressure Measurement. AAMI 32nd Annual Proceedings. 1997;32:40-41